Calb1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:116593 Wang T, et al., The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype. Mol Cell Neurosci. 2006 Oct;33(2):200-13
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:3843875
Gene symbol:	Calb1
Gene name:	calbindin 1

Antibody:	anti-Calbindin (AB1778)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

Specimen 2Ca & 2Ce: postnatal month 3 (more

)
Note: Fig. 2Ce is a higher magnification image of Fig. 2Ca.

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present		2Ca , 2Ce

Specimen 2Cb & 2Cf: postnatal month 3; Agtpbp1^pcd-3J/Agtpbp1^pcd-3J (more

)
Note: Fig. 2Cf is a higher magnification image of Fig. 2Cb.

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Absent		2Cb , 2Cf	Almost all Purkinje cells had degenerated in the mutant mice.

Specimen 7Aa & 7Ae: postnatal month 3 (more

)
Note: Fig. 7Ae is a higher magnification image of Fig. 7Aa.

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present		7Ae , 7Aa

Specimen 7Ab & 7Af: postnatal month 3; Agtpbp1^pcd-3J/Agtpbp1^pcd-3J (more

)
Note: Fig. 7Af is a higher magnification image of Fig. 7Ab.

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Absent		7Ab , 7Af	The mutant mice had lost essentially all cerebellar Purkinje cells compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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