Tg(CDX2-cre*)189Erf
Transgene Detail
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Symbol: |
Tg(CDX2-cre*)189Erf |
Name: |
transgene insertion 189, Eric R Fearon |
MGI ID: |
MGI:3843611 |
Synonyms: |
CDX2P9.5-G22Cre |
Transgene: |
Tg(CDX2-cre*)189Erf Location: unknown
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Alliance: |
Tg(CDX2-cre*)189Erf page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(CDX2-cre*)189Erf expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Homolog in Mouse |
Note |
human |
CDX2 (1045) |
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Mutation details: The CDX2P9.5-G22Cre transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a nuclear-localized Cre recombinase gene modified with a 22 guanine nucleotide repeat tract between its initiating methionine (ATG) codon and the remainder of the Cre-coding region, and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic founders (line 189) were found to have approximately 80 copies of the transgene and were bred to C57BL/6J mice.
(J:148161)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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CDX2
(human)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:148161 Akyol A, et al., Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nat Methods. 2008 Mar;5(3):231-3 |
All: |
8 reference(s) |
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