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Gene Expression Data
Assay Details
Assay
Reference: J:4086 Hui CC, et al., A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet. 1993 Mar;3(3):241-6
Assay type: RNA in situ
MGI Accession ID: MGI:3843368
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Probe: pGli-3a
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3c (left): embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: embryo Present 3c (left)
Specimen 3c (right): embryonic day 12.0; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: embryo Trace 3c (right) Authors that the level of expression was very low in the mutant embryo compared to the wild type littermate.
Specimen 5a/b: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Strong 5a/b
TS17: hindlimb bud ectoderm Absent 5a/b
Specimen 5c/d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb interdigital region mesenchyme Present 5c/d Expression in the interdigital mesenchyme, between the precartilaginous rays of the future digits.
TS22: hindlimb digit mesenchyme Present Regionally restricted 5c/d Expression in the interzonal mesenchyme, which gives rise to the joints.
TS22: foot cartilage condensation Absent 5c/d
Specimen 5e/f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: diencephalon ventricular layer Strong Regionally restricted 5e/f Authors report strong expression in both dorsal and ventral ventricular zones of the forebrain.
TS22: telencephalon ventricular layer Strong Regionally restricted 5e/f Authors report strong expression in both dorsal and ventral ventricular zones of the forebrain.
TS22: metencephalon ventricular layer Present Regionally restricted 5e/f Expression in the mesencephalon and metencephalon confined to dorsal ventricular zones.
TS22: midbrain ventricular layer Present Regionally restricted 5e/f Expression in the mesencephalon and metencephalon confined to dorsal ventricular zones.
TS22: nasal cavity Present Regionally restricted 5e/f Expression in the subepidermal mesenchyme of the nasal cavity and otic capsule.
TS22: otic capsule Present Regionally restricted 5e/f Expression in the subepidermal mesenchyme of the nasal cavity and otic capsule.
TS22: dental papilla Present Regionally restricted 5e/f Expression in the mesenchyme of the dental papillae and whisker follicles.
TS22: vibrissa follicle Present Regionally restricted 5e/f Expression in the mesenchyme of the dental papillae and whisker follicles.
TS22: intervertebral disc Present 5e/f Expression in the intervertebral disk anlage and in the sternal cartilage.
TS22: sternum Present 5e/f Expression in the intervertebral disk anlage and in the sternal cartilage.
Specimen 5g/h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal cavity Present Regionally restricted 5g/h Expression in the subepidermal mesenchyme of the nasal cavity and otic capsule.
TS22: otic capsule Present Regionally restricted 5g/h Expression in the subepidermal mesenchyme of the nasal cavity and otic capsule.
TS22: head Present Regionally restricted 5g/h Authors report expression in the mesenchyme surrounding the centrum.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/04/2024
MGI 6.13 		The Jackson Laboratory