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Gene Expression Data
Assay Details
Assay
Reference: J:90575 Nishino J, et al., Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J. 2004 May 5;23(9):1998-2008
Assay type: RNA in situ
MGI Accession ID: MGI:3843255
Gene symbol: Metrn
Gene name: meteorin, glial cell differentiation regulator
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 2A Expression was detected in all cell layers of the developing retina.

Specimen 2B & 2C: embryonic day 14.5 (more )
Note: Fig. 2C is a higher magnification image of Fig. 2B.
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C , 2B Expression was restricted to the external layer, where the retinal progenitor cells are located. No staining was detected in the inner layer (postmitotic neurons).

Specimen 2D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 2D Expression was detected in all layers in the spinal cord.

Specimen 2E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2E Expression was limited to the ventricular zone and was not detected in the mantle layer.

Specimen 2F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 2F Expression was detected in migrating neural crest in the peripheral nervous system.
TS15: peripheral nervous system Present Regionally restricted 2F Expression was detected in migrating neural crest in the peripheral nervous system.

Specimen 2G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Regionally restricted 2G Expression was detected in nerve roots, the site of Schwann cell progenitors.

Specimen 2I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present Regionally restricted 2I Expression was detected in the newly emergent satellite glial cells and in Schwann cells, but was not apparent in neurons.

Specimen 2K: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: telencephalon Present Regionally restricted 2K Expression was detected in the subventricular zone of the lateral ventricle. Expression was not detected in the parenchyma.
TS28: corpus callosum Present 2K

Specimen 2M: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 2M Expression was detected in the radial glia but not in the Purkinje cells.
TS28: cerebellum internal granule cell layer Absent 2M Expression was not detected in astrocytes in the inner granule cell layer.

Specimen 2O: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord ventricular layer Present Regionally restricted 2O Expression was detected in radial glia.

Specimen 2Q: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord mantle layer Present Regionally restricted 2Q Expression was detected in astrocytes.

Specimen S1A & S1D: embryonic day 13.5 (more )
Note: Fig. S1D is a higher magnification image of Fig. S1A.
Structure Level Pattern Image Note
TS21: spinal cord ventricular layer Present Regionally restricted S1A , S1D Expression is detected in along the entire dorsoventral axis of the ventricular zone.
TS21: spinal cord mantle layer Present Regionally restricted S1A , S1D A few cells have started to migrate toward the ventral portion of the mantle layer.

Specimen S1G & S1J: embryonic day 14.5 (more )
Note: Fig. S1J is a higher magnification image of S1G.
Structure Level Pattern Image Note
TS22: spinal cord ventricular layer Present Regionally restricted S1J , S1G Expression was detected in many cells in the ventricular zone.
TS22: spinal cord mantle layer Present Regionally restricted S1G , S1J Expression was detected in the ventral region of the mantle layer.

Specimen S2A & S2B: embryonic day 14.5 (more )
Note: Fig. S2B is a higher magnification image of Fig. S2A.
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present S2A , S2B
TS22: ganglionic eminence Present Regionally restricted S2A , S2B Expression was detected in the ventricular zone of the ganglionic eminence but not in the subventricular zone.

Specimen S2I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Absent S2I Expression was not detected in the prospective amygdala.

Specimen S3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum ventricular layer Present S3A

Specimen S3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebellum Present Regionally restricted S3C Expression was detected in migrating glial precursors.

Specimen S3E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum Present S3E

Specimen S3G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S3G

Specimen S3H & S3I: postnatal adult (more )
Note: Fig. S3I is a higher magnification image of S3H.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted S3I , S3H Expression was detected in Bergmann glial cells in the Purkinje cell layer.

Specimen S3J: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: retina Present S3J

Specimen S3K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S3K Expression was detected in the inner granular layer where Muller glia cell bodies exist.
TS28: retina ganglion cell layer Absent S3K Expression is not detected in astrocytes in the ganglion cell layer.

Specimen S3M: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: sciatic nerve Present Regionally restricted S3M Expression was detected in Schwann cells in the sciatic nerve.

Specimen S3O: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: trigeminal ganglion Absent S3O Expression was not detected in the satellite glia in the trigeminal sensory ganglia.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory