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Gene Expression Data
Assay Details
Assay
Reference: J:119856 Yang ZZ, et al., Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice. Mol Cell Biol. 2005 Dec;25(23):10407-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3843048
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: Anti-Pecam
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Present Regionally restricted 5B Expression was detected in fine vessels (capillaries) in the neuroepithelium of the hindbrain.

Specimen 5D: embryonic day 12.5; Akt1tm1Hem/Akt1tm1Hem, Akt3tm1Hem/Akt3tm1Hem (more )
Structure Level Pattern Image Note
TS20: blood vessel Present Regionally restricted 5D Fine vessels were scarce in the double knockout embryos.

Specimen 5F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: branchial arch artery Present Regionally restricted 5F Expression was detected in the first, second, and third arch arteries.
TS20: blood vessel Present Regionally restricted 5F Expression was detected in small vessels in mesenchymal tissue.

Specimen 5H: embryonic day 12.5; Akt1tm1Hem/Akt1tm1Hem, Akt3tm1Hem/Akt3tm1Hem (more )
Structure Level Pattern Image Note
TS20: branchial arch artery Present Regionally restricted 5H Expression was detected in the mutant, but the large arch arteries were fused or dilated and could not be distinguished.
TS20: blood vessel Present Regionally restricted 5H Fine vessels were scarce in the double knockout embryos.

Specimen 5I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: extraembryonic vascular system Present Regionally restricted 5I Expression was detected in the fetal vessels in the labyrinth.

Specimen 5J: embryonic day 12.5; Akt1tm1Hem/Akt1tm1Hem, Akt3tm1Hem/Akt3tm1Hem (more )
Structure Level Pattern Image Note
TS20: extraembryonic vascular system Present Regionally restricted 5J The fetal vessels in the labyrinth are rare in the double knockout.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory