Gene Expression Data
Assay Details
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Assay
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Reference:
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J:142494
Nakazaki H, et al., Transcriptional regulation by Pax3 and TGFbeta2 signaling: a potential gene regulatory network in neural crest development. Int J Dev Biol. 2009;53(1):69-79
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3842390
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Gene symbol:
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Neurog2
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Gene name:
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neurogenin 2
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Probe:
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Ngn2 probe8
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
(i):
embryonic day 10.0
(more  )
Specimen
(i):
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (i)
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Expression in the dorsal and ventral neural tube.
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Specimen
(ii):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Mutant Allele(s):
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Tgfb2tm1Doe/Tgfb2tm1Doe
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (ii)
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Expression decreased in dorsal neural tube and increased in ventral neural tube compared to wild type.
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Specimen
(iii):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Mutant Allele(s):
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Pax3Sp/Pax3Sp
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (iii)
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Reduced expression in the dorsal region of the neural tube.
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Specimen
(iv):
embryonic day 10.0; Pax3Sp/Pax3 +
(more )
Specimen
(iv):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Mutant Allele(s):
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Pax3Sp/Pax3+
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (iv)
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Expression reduced in both dorsal and ventral neural tube regions.
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Specimen
(v):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Mutant Allele(s):
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Pax3Sp/Pax3+
Tgfb2tm1Doe/Tgfb2+
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (v)
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Reduced expression in the dorsal region of the neural tube.
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Specimen
(vi):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * Black Swiss * C57BL/6J
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Mutant Allele(s):
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Pax3Sp/Pax3+
Tgfb2tm1Doe/Tgfb2tm1Doe
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
2B (vi)
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Expresssion in ventral regions simlar to those seen in TGFb2-/- embryos; dorsal region expression closer to wild type.
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Analysis Tools
