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Gene Expression Data
Assay Details
Assay
Reference: J:102999 Castellini M, et al., Palm is expressed in both developing and adult mouse lens and retina. BMC Ophthalmol. 2005 Jun 21;5:14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3841616
Gene symbol: Palm
Gene name: paralemmin
Antibody: Anti-Palm
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1A,C: embryonic day 9.5 (more )
Note: Fig. 1C is the merged image of Fig. 1A and B.
Structure Level Pattern Image Note
TS15: embryo ectoderm Present Regionally restricted 1A , 1C Expression was detected in head ectoderm overlying the optic vesicle.
TS15: optic vesicle Present 1A , 1C

Specimen 1D,F: embryonic day 10.5 (more )
Note: Fig. 1F is the merged image of Fig. 1D and E.
Structure Level Pattern Image Note
TS17: eye Present Regionally restricted 1F , 1D Expression was detected at relatively similar levels in the presumptive neural retina, retinal pigmented epithelium, corneal epithelium and lens vesicle.
TS17: lens pit Present 1F , 1D Expression was detected in the lens vesicle.
TS17: optic cup inner layer Present 1D , 1F Expression was detected in the presumptive neural retina.
TS17: optic cup outer layer Present 1D , 1F Expression was detected in the retinal pigmented epithelium.

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Weak
TS19: neural retinal epithelium Present
TS19: perioptic mesenchyme Present Regionally restricted Expression was detected in the periocular mesenchyme.

Specimen 1G,I: embryonic day 12.5 (more )
Note: Fig. 1I is the merged image of Fig. 1G and H.
Structure Level Pattern Image Note
TS20: neural retinal epithelium Strong Regionally restricted 1I , 1G Intense expression was detected at the vitreal surface of the neural retina.
TS20: lens vesicle Present Regionally restricted 1G , 1I Expression was detected in the lens epithelial and fiber cell membranes.
TS20: lens vesicle epithelium Present 1G , 1I

Specimen 2A,C: embryonic day 14.5 (more )
Note: Fig. 2C is the merged image of Fig. 2A and B.
Structure Level Pattern Image Note
TS22: lens epithelium Present Regionally restricted 2A , 2C Expression was detected at cell membranes.
TS22: lens fiber Present Regionally restricted 2A , 2C Expression was detected at cell membranes.

Specimen 2E,G: postnatal week 1 (more )
Note: Fig. 2G is the merged image of Fig. 2E and F.
Structure Level Pattern Image Note
TS28: lens epithelium Present Regionally restricted 2E , 2G Expression was detected at cell membranes.
TS28: lens fiber Present Regionally restricted 2E , 2G Expression was detected at cell membranes.

Specimen 2H: postnatal week 25 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Present Regionally restricted 2H Expression was detected at cell membranes.
TS28: lens fiber Present Regionally restricted 2H Expression was detected at cell membranes.

Specimen 4A,C: embryonic day 16.5 (more )
Note: Fig. 4C is the merged image of Fig. 4A and B.
Structure Level Pattern Image Note
TS24: neural retina Present Regionally restricted 4A , 4C Expression was detected in the cell bodies of differentiating ganglion cells and undifferentiated neural precursors. Slightly stronger expression was detected in the axons of the developing inner plexiform layer.

Specimen 4D,F: postnatal day 1 (more )
Note: Fig. 4F is the merged image of Fig. 4D and E
Structure Level Pattern Image Note
TS27: retina inner plexiform layer Present 4F , 4D

Specimen 4G,I: postnatal week 1 (more )
Note: Fig. 4I is the merged image of Fig. 4G and H.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 4G , 4I Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina inner nuclear layer Present 4G , 4I Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina inner plexiform layer Present 4G , 4I Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina outer plexiform layer Present 4I , 4G
TS28: retina outer nuclear layer Weak Regionally restricted 4I , 4G Staining was much less on the photoreceptor cell bodies of the outer nuclear layer than in any other retinal layer.

Specimen 4J,L: postnatal week 2 (more )
Note: Fig. 4L is the merged image of Fig. 4J and K.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 4J , 4L Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina inner nuclear layer Present 4J , 4L Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina inner plexiform layer Present 4J , 4L Expression intensity was similar in the inner plexiform layer, ganglion cell bodies and inner nuclear layer.
TS28: retina outer nuclear layer Present Regionally restricted 4J , 4L Staining was much less on the photoreceptor cell bodies of the outer nuclear layer than in any other retinal layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory