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Gene Expression Data
Assay Details
Assay
Reference: J:31835 Weinmaster G, et al., A homolog of Drosophila Notch expressed during mammalian development. Development. 1991 Sep;113(1):199-205
Assay type: RNA in situ
MGI Accession ID: MGI:3840275
Gene symbol: Notch1
Gene name: notch 1
Probe: SN6-15
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: neural tube Present 3A
Specimen 3B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dorsal root ganglion Very strong 3B
TS16: future hindbrain Very strong 3B
TS16: future midbrain Very strong 3B
TS16: future spinal cord Very strong 3B
TS16: telencephalon Very strong 3B
Specimen 3C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Very strong 3C
TS20: eye Very strong 3C
TS20: hindbrain Very strong 3C
TS20: midbrain Very strong 3C
TS20: telencephalon Very strong 3C
TS20: trigeminal ganglion Very strong 3C
Specimen 3D,E: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: hindbrain ventricular layer Very strong 3D/E Very high expression in the proliferative zone lining the 4th ventricle.
Specimen 3F: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: brain Present Regionally restricted 3F Expression in the proliferative zone of the brain.
TS24: ear Present 3F
TS24: eye Present 3F
TS24: trigeminal ganglion Present 3F
TS24: tooth Strong Regionally restricted 3F Authors report strong expression in tooth buds.
Specimen 3G,H: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: trigeminal ganglion Present 3G/H
TS24: cochlea Present Regionally restricted 3G/H Expression in sensory hair cells in the cochlea.
TS24: skeleton Absent 3G/H No expression in osteogenic and cartilagenous tissues.
Specimen 3I,J: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lens Strong Regionally restricted 3I/J Strong expression in proliferating cells of the retinal layer and lens.
TS24: retina Strong Regionally restricted 3I/J Strong expression in proliferating cells of the retinal layer and lens.
Specimen 3K: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: thymus Present 3K
TS24: metanephros Strong 3K
TS24: salivary gland Strong 3K
TS24: vibrissa follicle Strong 3K
Specimen 3L,M: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Present 3L/M
TS24: vertebra Absent 3L/M No expression in osteogenic and cartilagenous tissues.
Specimen E18 not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: embryo Present Regionally restricted Authors report a "complex" pattern of expression.
Specimen 3N,O: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hair bulb Strong Regionally restricted 3N/O Strong expression in matrix cells of the hair bulb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory