Sim1tm1.1(cre)Gld
Targeted Allele Detail
|
Symbol: |
Sim1tm1.1(cre)Gld |
Name: |
single-minded family bHLH transcription factor 1; targeted mutation 1.1, Martyn Goulding |
MGI ID: |
MGI:3839912 |
Synonyms: |
Sim1Cre |
Gene: |
Sim1 Location: Chr10:50770850-50865248 bp, + strand Genetic Position: Chr10, 24.87 cM, cytoband B3-B4
|
Alliance: |
Sim1tm1.1(cre)Gld page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:147245
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Sim1tm1.1(cre)Gld expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Sim1 (MGI:98306) |
|
|
|
|
Mutation details: A cre gene followed by an frt flanked neo cassette were inserted via homologous recombination replacing the first exon. The neo cassette was then removed by Flp mediated recombination. At E11.5 Cre activity mirrors the pattern of endogenous Sim1 mRNA expression.
(J:147245)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Sim1
(mouse)
|
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Sim1 Mutation: |
52 strains or lines available
|
|
Original: |
J:147245 Zhang Y, et al., V3 spinal neurons establish a robust and balanced locomotor rhythm during walking. Neuron. 2008 Oct 9;60(1):84-96 |
All: |
13 reference(s) |
|