Tg(MPO*-463A)1Wfr
Transgene Detail
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| Symbol: |
Tg(MPO*-463A)1Wfr |
| Name: |
transgene insertion 1, Wanda F Reynolds |
| MGI ID: |
MGI:3839893 |
| Synonyms: |
MPOA |
| Transgene: |
Tg(MPO*-463A)1Wfr Location: unknown
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| Alliance: |
Tg(MPO*-463A)1Wfr page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(MPO*-463A)1Wfr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
MPO (4353) |
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Mutation details: A construct containing a 32-kb BST11071 restriction fragment including the human gene with 7 kb of upstream and 11 kb of downstream sequence, and containing the human functional upstream promoter polymorphism, -463GA (A allele) was used to create transgenic mice. This polymorphism is contained within a conserved sequence recognized by various nuclear receptors. Only one founder mouse was obtained.
(J:130052)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:130052 Kumar AP, et al., Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism. J Biol Chem. 2004 Feb 27;279(9):8300-15 |
| All: |
3 reference(s) |
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Analysis Tools
