Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Mt1-STC1)Gdm
Name:	transgene insertion, Gabriel E DiMattia
MGI ID:	MGI:3839135
Transgene:	Tg(Mt1-STC1)Gdm  Location: unknown
Alliance:	Tg(Mt1-STC1)Gdm page

Strain of Origin:

C57BL/6 x CBA

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Mt1-STC1)Gdm expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human STC1 (6781) Stc1  (MGI:109131)   Mutation details: The mouse Mt1 minimal promoter was used to drive expression of a human STC1 construct made up of a genomic fragment containing 93bp of the 5' UTR, exon 1, intron 1, exon 2, and intron 2. This was fused to a human cDNA containing exon 3 and 573 bp of exon 4. The remainder of the construct was made up of 800 bp from the 3' UTR of the human GH gene. (J:109144)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:109144 Varghese R, et al., Overexpression of human stanniocalcin affects growth and reproduction in transgenic mice. Endocrinology. 2002 Mar;143(3):868-76
All:	4 reference(s)