About   Help   FAQ
Eif2s2Gt(XH413)Byg
Gene trapped Allele Detail
Summary
Symbol: Eif2s2Gt(XH413)Byg
Name: eukaryotic translation initiation factor 2 subunit 2 beta; gene trap XH413, BayGenomics
MGI ID: MGI:3838881
Synonyms: Eif2s2Trap
Gene: Eif2s2  Location: Chr2:154713330-154734826 bp, - strand  Genetic Position: Chr2, 76.89 cM
Alliance: Eif2s2Gt(XH413)Byg page
Mutation
origin
Mutant Cell Line:  XH413
Germline Transmission:  Earliest citation of germline transmission: J:146879
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation details: The gene trap vector pGT1Lxf inserted into the first intron. Reduced transcript expression was confirmed by quantitative RT-PCR on liver, testes, and spleen extracts. (J:146879)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eif2s2 Mutation:  96 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:146879 Heaney JD, et al., Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice. Hum Mol Genet. 2009 Apr 15;18(8):1395-404
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory