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Gene Expression Data
Assay Details
Assay
Reference: J:143211 Kwakowsky A, et al., GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3837351
Gene symbol: Gabbr2
Gene name: gamma-aminobutyric acid type B receptor subunit 2
Antibody: anti-GABA-BR2
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 3M Expression is in the lens epithelial cells comprising the lens vesicle and is enriched at the luminal (apical) ends.
Specimen 3N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens epithelium Strong 3N
TS24: lens fiber Strong Regionally restricted 3N Expression is at the tips of secondary fiber cells of the equatorial region.
Specimen 3O: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lens epithelium Present 3O
TS27: lens fiber Present 3O
Specimen 4I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens epithelium Present 4I Expression is in the apical/basal membranes of lens epithelial cells.
TS24: lens fiber Present Regionally restricted 4I Expression is in the apical ends of equatorial fibers and their basal tips forming the posterior lens suture.
Specimen 4J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens Present Regionally restricted 4J Expression is in the posterior lens pole with the forming suture.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory