Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lrrtm1tm1Amcr
Name:	leucine rich repeat transmembrane neuronal 1; targeted mutation 1, Ann Marie Craig
MGI ID:	MGI:3836788
Gene:	Lrrtm1  Location: Chr6:77219672-77234774 bp, + strand  Genetic Position: Chr6, 33.89 cM
Alliance:	Lrrtm1tm1Amcr page

Germline Transmission:	Earliest citation of germline transmission: J:145907
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 which encodes the entire open reading frame was replaced with an IRES-tauLacZ followed by a floxed neo cassette via homologous recombination. The neo cassette was later removed leaving behind a single loxP site. (J:145907)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrrtm1 Mutation:	36 strains or lines available

Original:	J:145907 Linhoff MW, et al., An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron. 2009 Mar 12;61(5):734-49
All:	3 reference(s)