Tg(Chat-cre)GM24Gsat
Transgene Detail
|
Symbol: |
Tg(Chat-cre)GM24Gsat |
Name: |
transgene insertion GM24, GENSAT Project at Rockefeller University |
MGI ID: |
MGI:3836624 |
Synonyms: |
GM24, Tg(Chat-cre)24Gsat |
Transgene: |
Tg(Chat-cre)GM24Gsat Location: unknown
|
Alliance: |
Tg(Chat-cre)GM24Gsat page
|
|
Strain of Origin: |
FVB/N
|
Project Collection: |
GENSAT
|
|
Transgene Type: |
|
Transgenic (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Tg(Chat-cre)GM24Gsat expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Chat (MGI:88392) |
|
|
|
|
Mutation details: A Cre-expression cassette, followed by a polyadenylation sequence to terminate transcription of the fusion transcript immediately after the recombinase gene, was inserted into a BAC vector at the initiating ATG codon in the first coding exon of the gene. The Cre expression pattern matches adult Chat gene expression (all cholinergic neurons) and is limited to motor neurons, with minimal expression in forebrain structures.
(J:145110)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Chat
(mouse)
|
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:145110 Gong S, et al., Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci. 2007 Sep 12;27(37):9817-23 |
All: |
32 reference(s) |
|