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Gene Expression Data
Assay Details
Assay
Reference: J:64329 Welsh IC, et al., Loss of late primitive streak mesoderm and interruption of left-right morphogenesis in the Ednrb(s-1Acrg) mutant mouse. Dev Biol. 2000 Sep 1;225(1):151-68
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3836575
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Direct Detection
Assay notes: Tissues were fixed in 0.2% glutaraldehyde.
Results
Specimen 3A: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: yolk sac Present Regionally restricted 3A Expression was detected in endothelial precursors.
Specimen 3B: embryonic day 9.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: yolk sac Present Regionally restricted 3B Expression was detected in endothelial precursors, but the cells remained isolated, giving the yolk sac a peppered appearance.
Specimen 3C: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: yolk sac Present Regionally restricted 3C Expression was detected in endothelial precursors.
Specimen 3D: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: cardiovascular system Present Regionally restricted 3D Expression was detected in endothelial precursors.
Specimen 3E: embryonic day 9.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: cardiovascular system Present Regionally restricted 3E Expression was detected in endothelial precursors. Phenotypic alterations were detected in the mutant in the endocardial tube of the heart and vascular connections of the anterior cardinal vein. The intersomitic vessels did not form in the mutant.
Specimen 3F: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: cardiovascular system Present Regionally restricted 3F Expression was detected in endothelial precursors.
Specimen 3G: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: primitive streak Present Regionally restricted 3G Expression was detected in the proximolateral region of the primitive streak.
TS14: extraembryonic component Present Regionally restricted 3G Expression was detected in the extraembryonic mesoderm.
Specimen 3H: embryonic day 9.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: primitive streak Present Regionally restricted 3H Expression was detected in the proximolateral region of the primitive streak.
TS14: extraembryonic component Present Regionally restricted 3H Expression was detected in the extraembryonic mesoderm.
TS14: mesenchyme derived from lateral plate Present Regionally restricted 3H Expression accumulated in the posterior lateral mesoderm of the mutant.
Specimen 3I: embryonic day 8.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: dorsal aorta Present 3I
Specimen 5A: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: endocardial tube Present 5A
Specimen 5B: embryonic day 9.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: endocardial tube Present 5B
Specimen 5C: embryonic day 8.75; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: endocardial tube Present 5C
Specimen 5D: embryonic day 9.5; Ednrbs-1Acrg/Ednrbs-1Acrg, Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: endocardial tube Present 5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory