Tg(KRT14-HPV16E6*)512Agri
Transgene Detail
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| Symbol: |
Tg(KRT14-HPV16E6*)512Agri |
| Name: |
transgene insertion 512, Anne E Griep |
| MGI ID: |
MGI:3835831 |
| Synonyms: |
K14E6delta146-151 |
| Transgene: |
Tg(KRT14-HPV16E6*)512Agri Location: unknown
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| Alliance: |
Tg(KRT14-HPV16E6*)512Agri page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The human promoter was used to drive expression of a human papilloma virus 16 (HPV16) genomic fragment encoding E6 but lacking amino acids 146 through 151 (the last six amino acids of the PDZ domain) with the E6/E7 translation termination linker and polyA sequences in the epithelium. Six lines were generated with line 512 selected as the representative line.
(J:86871)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:134744 Nguyen ML, et al., The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo. J Virol. 2003 Jun;77(12):6957-64 |
| All: |
5 reference(s) |
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Analysis Tools
