Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Eaf2tm1Zhow
Name:	ELL associated factor 2; targeted mutation 1, Zhou Wang
MGI ID:	MGI:3834174
Synonyms:	U19-
Gene:	Eaf2  Location: Chr16:36613246-36695275 bp, - strand  Genetic Position: Chr16, 26.05 cM
Alliance:	Eaf2tm1Zhow page

Germline Transmission:	Earliest citation of germline transmission: J:145228
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:145228)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

List all tumor models in MMHCdb carrying Eaf2tm1Zhow

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eaf2 Mutation:	19 strains or lines available

Original:	J:145228 Xiao W, et al., U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia. Oncogene. 2008 Mar 6;27(11):1536-44
All:	8 reference(s)