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Shhtm1Tshir
Targeted Allele Detail
Summary
Symbol: Shhtm1Tshir
Name: sonic hedgehog; targeted mutation 1, Toshihiko Shiroishi
MGI ID: MGI:3833929
Gene: Shh  Location: Chr5:28661838-28672099 bp, - strand  Genetic Position: Chr5, 14.39 cM
Alliance: Shhtm1Tshir page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145170
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first 35 bp following the translation initiation site were replaced with a d2EGFP and neo cassette. (J:145170)
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Shh Mutation:  45 strains or lines available
References
Original:  J:145170 Amano T, et al., Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription. Dev Cell. 2009 Jan;16(1):47-57
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory