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Tg(Acta2-cre/ERT2)51Pcn
Transgene Detail
Summary
Symbol: Tg(Acta2-cre/ERT2)51Pcn
Name: transgene insertion 51, Pierre Chambon
MGI ID: MGI:3831911
Synonyms: SMA-Cre-ERT2, tg(Sma-CreERT2)51Pcn
Transgene: Tg(Acta2-cre/ERT2)51Pcn  Location: unknown  
Alliance: Tg(Acta2-cre/ERT2)51Pcn page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Acta2-cre/ERT2)51Pcn expression driven by 1 gene
 
Mutation detailsA construct containing cre fused to ERT2 followed by an frt flanked PGK-neo cassette was inserted at the initiation codon of Acta2 in a 175 kb mouse BAC. Tamoxifen-induced cre activity was seen in smooth muscle cells. (J:144642)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acta2 (mouse)
Summary of all recombinase alleles driven by Acta2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:144642 Wendling O, et al., Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis. 2009 Jan;47(1):14-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory