Pot1btm1Schg
Targeted Allele Detail
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| Symbol: |
Pot1btm1Schg |
| Name: |
protection of telomeres 1B; targeted mutation 1, Sandy Chang |
| MGI ID: |
MGI:3831880 |
| Synonyms: |
Pot1brec |
| Gene: |
Pot1b Location: Chr17:55958951-56019628 bp, - strand Genetic Position: Chr17, 28.93 cM, cytoband D
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| Alliance: |
Pot1btm1Schg page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:144553
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| Parent Cell Line: |
TC1/TC-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A lox P site followed by an frt flanked neo cassette were inserted before exon 3 and a second loxP site was inserted after exon 4 via homologous recombination.
(J:144553)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pot1b Mutation: |
38 strains or lines available
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| Original: |
J:144553 He H, et al., Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Mol Cell Biol. 2009 Jan;29(1):229-40 |
| All: |
1 reference(s) |
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Analysis Tools
