Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc26a6tm1Smua
Name:	solute carrier family 26, member 6; targeted mutation 1, Shmuel Muallem
MGI ID:	MGI:3831563
Gene:	Slc26a6  Location: Chr9:108731239-108742117 bp, + strand  Genetic Position: Chr9, 59.63 cM, cytoband F2
Alliance:	Slc26a6tm1Smua page

Germline Transmission:	Earliest citation of germline transmission: J:144457
Parent Cell Line:	SM1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A fragment including exons 7 - 9 was replaced with a neo cassette via homologous recombination. (J:144457)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc26a6 Mutation:	31 strains or lines available

Original:	J:144457 Wang Y, et al., Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis. EMBO J. 2006 Nov 1;25(21):5049-57
All:	5 reference(s)