Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kalrntm1.1Npl
Name:	kalirin, RhoGEF kinase; targeted mutation 1.1, Neuropeptide Laboratory
MGI ID:	MGI:3831292
Synonyms:	Kal7KO, Kalrntm1.1Riem
Gene:	Kalrn  Location: Chr16:33789443-34393647 bp, - strand  Genetic Position: Chr16, 24.27 cM
Alliance:	Kalrntm1.1Npl page

Germline Transmission:	Earliest citation of germline transmission: J:142364
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Modified isoform(s)) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove the exon specific for isoform 7. The absence of protein expression of Kalrn7 and deltaKalrn7 was confirmed by western blot analysis of cerebral cortex extracts. (J:142364)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kalrn Mutation:	170 strains or lines available

Original:	J:142364 Ma XM, et al., Kalirin-7 is required for synaptic structure and function. J Neurosci. 2008 Nov 19;28(47):12368-82
All:	8 reference(s)