Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il20rbtm1Uwe
Name:	interleukin 20 receptor beta; targeted mutation 1, Ursula Maria Wegenka
MGI ID:	MGI:3830304
Synonyms:	IL20R2-
Gene:	Il20rb  Location: Chr9:100339772-100368526 bp, - strand  Genetic Position: Chr9, 52.66 cM
Alliance:	Il20rbtm1Uwe page

Germline Transmission:	Earliest citation of germline transmission: J:143497
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A total of 1.7 kb of genomic sequence, including start codon, signal peptide, 1.3 kb upstream of exon 1, and 350 bp of the first intron were replaced with a neomycin selection cassette. Gene inactivation was confirmed by a lack of signal in RT-PCR of liver extracts from mice injected with LPS. (J:143497)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il20rb Mutation:	31 strains or lines available

Original:	J:143497 Wahl C, et al., IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses. J Immunol. 2009 Jan 15;182(2):802-10
All:	4 reference(s)