Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-ALPP)Fawa
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Fan Wang
MGI ID:	MGI:3829026
Synonyms:	Rosa26RCAG-hPLAP
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-ALPP)Fawa page

Germline Transmission:	Earliest citation of germline transmission: J:143278
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: The human gene driven by the CAG promoter was cloned downstream of a floxed neo cassette and 4 polyadenylation sequences (STOP signal). Expression of the human gene can only be achieved by cre-mediated removal of the floxed neo STOP cassette. (J:143278, J:143859)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:143278 Que J, et al., Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16626-30
All:	5 reference(s)