Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfe2l1tm1Mym
Name:	nuclear factor, erythroid derived 2,-like 1; targeted mutation 1, Masayuki Yamamoto
MGI ID:	MGI:3828165
Synonyms:	Nrf1flox
Gene:	Nfe2l1  Location: Chr11:96708240-96720794 bp, - strand  Genetic Position: Chr11, 60.12 cM, cytoband D-E
Alliance:	Nfe2l1tm1Mym page

Germline Transmission:	Earliest citation of germline transmission: J:143468
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette followed by an IRES-EGFP replaces the non-coding portion of exon 4. (J:143468)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l1 Mutation:	39 strains or lines available

Original:	J:143468 Ohtsuji M, et al., Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes. J Biol Chem. 2008 Nov 28;283(48):33554-62
All:	10 reference(s)