Tg(ACTB-Lama5*G2/LAMA1)2Jhm
Transgene Detail
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| Symbol: |
Tg(ACTB-Lama5*G2/LAMA1)2Jhm |
| Name: |
transgene insertion 2, Jeffrey H Miner |
| MGI ID: |
MGI:3828062 |
| Synonyms: |
Mr5G2H |
| Transgene: |
Tg(ACTB-Lama5*G2/LAMA1)2Jhm Location: unknown
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| Alliance: |
Tg(ACTB-Lama5*G2/LAMA1)2Jhm page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(ACTB-Lama5*G2/LAMA1)2Jhm expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
LAMA1 (284217) |
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| mouse |
Lama5 (MGI:105382) |
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Mutation details: The chicken beta-actin promoter with the Rous sarcoma virus-long terminal repeat from the miw vector was used to drive ubiquitous expression of a fusion gene encoding the laminin alpha chain and first 2 laminin-type globular (LG) modules from Lama5 and LG modules 3-5 of human LAMA1. The line produced expresses the transgene at a higher level than in mice carrying Tg(CAG-Lama5*G2/LAMA1)1Jhm.
(J:119297)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:119297 Kikkawa Y, et al., Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function. Dev Biol. 2006 Aug 1;296(1):265-77 |
| All: |
1 reference(s) |
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Analysis Tools
