Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Cela1-cre/ERT2)1Stof
Name:	transgene insertion 1, Doris A Stoffers
MGI ID:	MGI:3820514
Synonyms:	ElastaseCreERT2, Tg(Ela1-Cre/ESR1)1Stof
Transgene:	Tg(Cela1-cre/ERT2)1Stof  Location: unknown
Alliance:	Tg(Cela1-cre/ERT2)1Stof page

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Cela1-cre/ERT2)1Stof expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note rat Cela1 (24331) Cela1  (MGI:95314)   Mutation details: A transgenic construct containing the rabbit Beta-globin (RBG) intron, a sequence encoding Cre/ESR1 (Cre recombinase fused to a mutant estrogen receptor ligand-binding domain (ERT2)) under the control of the acinar cell-specific rat elastase 1 (Cela1) promoter, and a rabbit Beta-globin polyadenylation cassette was made and injected into B6SJLF1 oocytes. (J:121254)

Activity:	Tissue activity of this recombinase allele
Driver:	Cela1 (rat) Summary of all recombinase alleles driven by Cela1. Comparative matrix view of recombinase activities Alliance rat Cela1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Cela1-cre/ERT2)1Stof

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:121254 Desai BM, et al., Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest. 2007 Apr;117(4):971-7
All:	16 reference(s)