Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxa11tm1Dmwe
Name:	homeobox A11; targeted mutation 1, Deneen M Wellik
MGI ID:	MGI:3814861
Synonyms:	Hoxa11eGFP
Gene:	Hoxa11  Location: Chr6:52219086-52222784 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance:	Hoxa11tm1Dmwe page

Germline Transmission:	Earliest citation of germline transmission: J:140709
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: An eGFP construct was inserted 18 bp downstream of the start site in exon 1 replacing most of exon 1. This was followed by an SV40 T-antigen stop sequence and a self-excising neo cassette in reverse orientation. Cre mediated excision of the neo cassette occurs in the testes. (J:140709)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	243 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxa11 Mutation:	11 strains or lines available

Original:	J:140709 Nelson LT, et al., Generation and expression of a Hoxa11eGFP targeted allele in mice. Dev Dyn. 2008 Nov;237(11):3410-6
All:	6 reference(s)