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Gene Expression Data
Assay Details
Assay
Reference: J:33250 Du H, et al., Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein. J Lipid Res. 1996 May;37(5):937-49
Assay type: RNA in situ
MGI Accession ID: MGI:3814426
Gene symbol: Lipa
Gene name: lysosomal acid lipase A
Probe: mLAL cDNA
Probe preparation: Antisense RNA
Results
Specimen 3a: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Strong 3a Expression is strong in all cell types and is intense in hepatoytes.
TS28: liver sinusoid Very strong Regionally restricted 3a Expression is in sinusoidal lining cells.

Specimen 3b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Strong 3b Expression is strong in all cell types and is intense in hepatoytes.
TS28: liver sinusoid Very strong Regionally restricted 3b Expression is in sinusoidal lining cells.

Specimen 3d: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thymus Strong Regionally restricted 3d Expression is in activated macrophages or component of the reticuloendothelial cells.
TS28: thymus cortex Moderate Uniform 3d
TS28: thymus medullary core Moderate Uniform 3d

Specimen 3e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Strong 3e
TS28: renal cortex Present Regionally restricted 3e Absent in the coritical rays.
TS28: renal corpuscle Absent 3e
TS28: renal medulla Absent 3e Absent in the medullary rays.

Specimen 3f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Strong 3f
TS28: renal cortex Present Regionally restricted 3f Absent in the coritical rays.
TS28: renal corpuscle Absent 3f
TS28: renal medulla Absent 3f Absent in the medullary rays.

Specimen 3h: postnatal adult (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent 3h Expression is in acinar cells, not in islet cells.
TS28: pancreatic acinus Strong 3h There was strong expression in the acinar cells.
TS28: pancreatic duct Absent 3h

Specimen 3j: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adrenal gland zona fasciculata Strong 3j
TS28: adrenal gland zona reticularis Strong 3j
TS28: adrenal gland zona glomerulosa Absent 3j
TS28: adrenal medulla Absent 3j

Specimen 3k: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestinal villus Strong Regionally restricted 3k Expression is in epithelial cells lining the villi (villous columnar enterocytes and goblet cells) and is absent in the glands at the base of the villi or in the lamina propria, muscularis mucosae, submucosa and muscularis externa.

Specimen 3l: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestinal villus Strong Regionally restricted 3l Expression is in epithelial cells lining the villi (villous columnar enterocytes and goblet cells) and is absent in the glands at the base of the villi or in the lamina propria, muscularis mucosae, submucosa and muscularis externa.

Specimen Table I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adrenal gland zona fasciculata Very strong
TS28: adrenal gland zona reticularis Very strong
TS28: renal proximal tubule Very strong
TS28: pancreatic acinus Very strong Expression is very strong in the acinar cells.
TS28: intestinal villus Strong Regionally restricted Expression is in epithelial cells.
TS28: hemolymphoid system Strong Regionally restricted Expression is in macrophages in the uterus. It is not present in lymphocytes and reticulocytes in the thymus.
TS28: liver Present Strong in hepatocytes and sinusoidal lining cells.
TS28: heart Absent
TS28: ovary Absent
TS28: salivary gland Absent
TS28: seminal vesicle Absent
TS28: spleen Absent
TS28: testis Absent
TS28: tongue Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory