Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:139189
Mitsiadis TA, et al., A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determination. Dev Biol. 2008 Aug 1;320(1):39-48
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:3814210
|
|
Gene symbol:
|
Tbx1
|
|
Gene name:
|
T-box 1
|
|
Probe:
|
Tbx1 cDNA2
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
|
Results
|
Specimen
1A:
embryonic day 12.5
(more  )
Note: This is a sagittal section.
Specimen
1A:
(close  )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a sagittal section.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: oral epithelium |
Strong |
Regionally restricted |
1A
|
During tooth initation, expression is present in the dental epithelial cells adjacent to the condensed mesenchyme.
|
Specimen
1B:
embryonic day 13.5
(more )
Note: This is a sagittal section.
Specimen
1B:
(close )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a sagittal section.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: molar epithelium |
Strong |
|
1B
|
Expression is present in the dental epithelial cells adjacent to the condensed mesenchyme.
|
Specimen
1C:
embryonic day 14.5
(more )
Note: This is a sagittal section.
Specimen
1C:
(close )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a sagittal section.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: molar enamel organ |
Present |
Regionally restricted |
1C
|
Expression is present in the inner dental epithelium, whereas other cells of the enamel organ are not labeled.
|
Specimen
1D:
embryonic day 17.5
(more )
Note: This is a sagittal section.
Specimen
1D:
(close )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 17.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a sagittal section.
|
Specimen
1F:
embryonic day 18.5
(more )
Note: This is a sagittal section.
Specimen
1F:
(close )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
This is a sagittal section.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: molar enamel organ |
Present |
Non-Uniform |
1F
|
There is strong expression in cells of the inner dental epithelium. There is faint expression in the epithelial root sheath. Expression levels decrease as differentiation occurs.
|
Specimen
7A:
embryonic day 13.0
(more )
Specimen
7A:
(close )
|
Genetic Background:
|
either: C57BL/6 or Swiss
|
|
Age:
|
embryonic day 13.0
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools