Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Tek-cre)2352Rwng
Name:	transgene insertion 2352, Rong Wang
MGI ID:	MGI:3810530
Synonyms:	Tg(Tek-cre)1Lfr, Tg(Tie2-Cre)2352, tie2-cre, Tie2Cre
Transgene:	Tg(Tek-cre)2352Rwng  Location: unknown
Alliance:	Tg(Tek-cre)2352Rwng page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Tek-cre)2352Rwng expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tek (MGI:98664)   Mutation details: A transgenic construct containing sequence encoding cre under the control of of the mouse Tek, endothelial-specific receptor tyrosine kinase (also known as Tie2), promoter was introduced into FVB/N donor eggs. Founder line 2352 was subsequently established. Cre recombinase expression is detected in most endothelial cells and blood islands of the extraembryonic mesoderm by embryonic day (E)7.5, in the dorsal aorta by E8.5 and is very strong in head vasculature by E9. (J:104401)

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (mouse) Summary of all recombinase alleles driven by Tek. Comparative matrix view of recombinase activities Alliance mouse Tek gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:104401 Braren R, et al., Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. J Cell Biol. 2006 Jan 2;172(1):151-62
All:	14 reference(s)