Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Egflamtm1Tfir
Name:	EGF-like, fibronectin type III and laminin G domains; targeted mutation 1, Takahisa Furukawa
MGI ID:	MGI:3808156
Synonyms:	Pikachurin-
Gene:	Egflam  Location: Chr15:7235601-7427876 bp, - strand  Genetic Position: Chr15, 3.5 cM
Alliance:	Egflamtm1Tfir page

Germline Transmission:	Earliest citation of germline transmission: J:138693
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1, which includes a start codon, was replaced with the PGK-neo cassette. The lack of expression in the mutant mouse retina was confirmed by northern blot and immunostaining. (J:138693)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Egflam Mutation:	60 strains or lines available

Original:	J:138693 Sato S, et al., Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation. Nat Neurosci. 2008 Aug;11(8):923-31
All:	5 reference(s)