Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Nr2e1-cre/ERT2)1Gsc
Name:	transgene insertion 1, Gunther Schutz
MGI ID:	MGI:3807544
Synonyms:	Tlx-CreERT2
Transgene:	Tg(Nr2e1-cre/ERT2)1Gsc  Location: unknown
Alliance:	Tg(Nr2e1-cre/ERT2)1Gsc page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Nr2e1-cre/ERT2)1Gsc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Nr2e1   Mutation details: This transgene consists of modified BAC containing the entire coding region of the Nr2e1 gene including flanking regulatory sequences 104 kb upstream and 30 kb downstream, and drives expression of a tamoxifen-inducible form of cre recombinase fusion protein which replaces part of exon 1 of the Nr2e1 gene. 6 lines were generated of which 3 lines are further analyzed. All three lines showed tamoxifen-inducible Cre activity in the developing forebrain. This is a representative record for all 3 lines. (J:138765)

Activity:	Tissue activity of this recombinase allele
Driver:	Nr2e1 (species not specified) Summary of all recombinase alleles driven by Nr2e1. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:138765 Liu HK, et al., The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone. Genes Dev. 2008 Sep 15;22(18):2473-8
All:	6 reference(s)