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Gene Expression Data
Assay Details
Assay
Reference: J:52877 Hemberger M, et al., Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in fetal and adult mouse tissues. Hum Mol Genet. 1999 Feb;8(2):229-36
Assay type: RNA in situ
MGI Accession ID: MGI:3807397
Gene symbol: Vbp1
Gene name: von Hippel-Lindau binding protein 1
Probe: Vbp1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen Not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS28: placenta Strong Regionally restricted There is strong expression in the labyrinthine region and in the chorionic plate, whereas the spongiotrophoblast cells and secondary giant cells show no expression.

Specimen 2B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS28: decidua Present 2B
TS28: placenta Strong Regionally restricted 2B There is strong expression in the labyrinthine region and in the chorionic plate, whereas the spongiotrophoblast cells and secondary giant cells show no expression.

Specimen 2F: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: embryo Present Non-Uniform 2F Expression was detected in most tissues of the mouse, albeit at different levels.
TS20: brain Present 2F This is one of the tissues with the highest expression level.
TS20: liver Present 2F This is one of the tissues with the highest expression level.
TS20: spinal cord Present 2F This is one of the tissues with the highest expression level.
TS20: lung Present 2F There is basal expression in this tissue.
TS20: primitive bladder Present 2F There is basal expression in this tissue.
TS20: intestine Moderate 2F

Specimen 2H: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: facial ganglion Strong 2H
TS23: nasal cavity epithelium Strong 2H
TS23: telencephalon Strong 2H

Specimen 2J: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina nuclear layer Strong Regionally restricted 2J There is strong expression in the inner neuroblastic cell layer.

Specimen 2L: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: spinal ganglion Strong 2L
TS23: vertebra Present 2L Expression is present in the perichondrium.
TS23: vertebral cartilage condensation Absent 2L There is no expression in the cartilage.

Specimen 2N: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: diaphragm Present 2N
TS23: heart atrium Present 2N
TS23: heart ventricle Present 2N
TS23: cardiac muscle tissue Moderate 2N
TS23: liver Moderate 2N
TS23: pancreas Moderate 2N
TS23: vibrissa Moderate 2N

Specimen 2P: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: liver Present 2P
TS23: adrenal gland Moderate 2P
TS23: metanephros Present 2P Expression in the kidney was less abundant than that in the adrenal gland.

Specimen Not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: embryo Present Non-Uniform Expression was detected in most tissues of the mouse, albeit at different levels.

Specimen Not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: embryo Present Non-Uniform Expression was detected in most tissues of the mouse, albeit at different levels.

Specimen Not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS28: placenta Present

Specimen Not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: embryo Present Non-Uniform Expression was detected in most tissues of the mouse, albeit at different levels.

Specimen Not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: embryo Present Non-Uniform Expression was detected in most tissues of the mouse, albeit at different levels.

Specimen Not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS28: placenta Present

Specimen Not shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: embryo Present Non-Uniform Expression was detected in most tissues of the mouse, albeit at different levels.

Specimen 3B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 3B Expression is present in the base of the crypts.

Specimen 3D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: large intestine epithelium Present 3D
TS28: large intestine crypt of lieberkuhn Absent 3D

Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 3F Expression is present in the subcortical cell layer.
TS28: dentate gyrus granule cell layer Present 3F

Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart Present Transcripts seem to be evenly distributed.
TS28: liver Present Transcripts seem to be evenly distributed.
TS28: lung Present Transcripts seem to be evenly distributed.
TS28: glomerular tuft Absent
TS28: renal tubule Strong
TS28: renal interstitium Strong There is strong expression in the kidney mesenchyme.
TS28: brain Present Non-Uniform Expression is uniform in most areas of the brain, except the hippocampus.
TS28: eye Present The expression pattern is the same as seen in the embryo.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory