Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Cyp17a1-icre)AJako
Name:	transgene insertion A, CheMyong Ko
MGI ID:	MGI:3807212
Synonyms:	Cyp17iCre, TCCre, Tg(Cyp17a1-cre)ACmk
Transgene:	Tg(Cyp17a1-icre)AJako  Location: unknown
Alliance:	Tg(Cyp17a1-icre)AJako page

Strain of Origin:

C57BL/6 x SJL

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Cyp17a1-icre)AJako expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Cyp17a1   Mutation details: The promoter was used to drive expression of a codon improved cre in the theca/interstitial cells of the ovary and Leydig cells of the testes. Three lines (lines A, B and C) were created. While all lines exhibit gonadal expression, line B and C exhibit extra-gonadal expression. (J:138920)

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp17a1 (species not specified) Summary of all recombinase alleles driven by Cyp17a1. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:138920 Bridges PJ, et al., Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis. Genesis. 2008 Sep 9;46(9):499-505
All:	19 reference(s)