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Tg(MSLN-TAg)299hLake
Transgene Detail
Summary
Symbol: Tg(MSLN-TAg)299hLake
Name: transgene insertion 299h, Richard A Lake
MGI ID: MGI:3804819
Synonyms: MexTAg
Transgene: Tg(MSLN-TAg)299hLake  Location: unknown  
Alliance: Tg(MSLN-TAg)299hLake page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details: A 1,850 bp fragment of the human mesothelin promoter drives expression of the SV40 large T antigen. This transgene is expressed in mesothelial cells. Transgenic line 299h carries approximately 100 copies of the transgene. In addition, lines 266s, 304i and 270i were also created. (J:116125)
Tumor Data
List all tumor models in MMHCdb carrying Tg(MSLN-TAg)299hLake
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:116125 Robinson C, et al., A novel SV40 TAg transgenic model of asbestos-induced mesothelioma: malignant transformation is dose dependent. Cancer Res. 2006 Nov 15;66(22):10786-94
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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12/30/2025
MGI 6.24 		The Jackson Laboratory