Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Gnrh1-cre)1Dlc
Name:	transgene insertion 1, Catherine Dulac
MGI ID:	MGI:3691288
Synonyms:	LHRH::Cre
Transgene:	Tg(Gnrh1-cre)1Dlc  Location: unknown
Alliance:	Tg(Gnrh1-cre)1Dlc page

Strain of Origin:

(C57BL/6 x CBA)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Gnrh1-cre)1Dlc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Gnrh1 (MGI:95789)   Mutation details: A cre-containing cassette including a nuclear localization signal and a polyadenylation sequence was inserted into the start codon of the LHRH gene by homologous recombination of the BAC, RP23-22J8 which includes 137 kb of 5' upstream and 73 kb downstream sequences around the LHRH coding sequence of the BAC. The modified BAC was then used to create transgenic mice. (J:115190)

Activity:	Tissue activity of this recombinase allele
Driver:	Gnrh1 (mouse) Summary of all recombinase alleles driven by Gnrh1. Comparative matrix view of recombinase activities Alliance mouse Gnrh1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

15 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:115190 Yoon H, et al., Olfactory inputs to hypothalamic neurons controlling reproduction and fertility. Cell. 2005 Nov 18;123(4):669-82
All:	35 reference(s)