Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Lck-betarec)1Abnd
Name:	transgene insertion 1, Antonio Bernad
MGI ID:	MGI:3802615
Synonyms:	Lck-beta, Tgbeta1
Transgene:	Tg(Lck-betarec)1Abnd  Location: unknown
Alliance:	Tg(Lck-betarec)1Abnd page

Strain of Origin:

C57BL/6 x CBA/J

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Lck-betarec)1Abnd expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Lck   Mutation details: The Lck promoter was used to drive immature T cell-specific expression of the prokaryotic beta-recombinase gene. Five lines where created, two with high levels of expression in the thymus (lines 1 and 2). Line 1 contains 15 transgene insertions whereas line 2 contains three. Expression levels were high in the thymus, lower in spleen and lymph nodes, and absent in liver and brain. (J:137580)

Activity:	Tissue activity of this recombinase allele
Driver:	Lck (species not specified) Summary of all recombinase alleles driven by Lck.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:137580 Servert P, et al., In vivo site-specific recombination using the beta-rec/six system. Biotechniques. 2008 Jul;45(1):69-78
All:	1 reference(s)