Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccdc42tm1(KOMP)Vlcg
Name:	coiled-coil domain containing 42; targeted mutation 1, Velocigene
MGI ID:	MGI:3800251
Synonyms:	Ccdc42KO, Ccdc42tm1Vlcg
Gene:	Ccdc42  Location: Chr11:68477863-68488777 bp, + strand  Genetic Position: Chr11, 41.85 cM
Alliance:	Ccdc42tm1(KOMP)Vlcg page
IMPC:	Ccdc42 gene page

Mutant Cell Lines:	10362A-D12, 10362A-F2, 10362B-D2
Germline Transmission:	Earliest citation of germline transmission: J:231668
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1   Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 10697bp between positions 68400713-68411409 of Chromosome 11 (Genome Build37). All seven exons (i.e. the entire coding sequence of the gene) were replaced with a lacZ reporter and neomycin resistance cassette. (J:136110, J:231668)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Ccdc42 Mutation:	23 strains or lines available

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	2 reference(s)