Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Akirin2tm1.1Aki
Name:	akirin 2; targeted mutation 1.1, Shizuo Akira
MGI ID:	MGI:3796163
Gene:	Akirin2  Location: Chr4:34550937-34566908 bp, + strand  Genetic Position: Chr4, 16.8 cM
Alliance:	Akirin2tm1.1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:130487
Parent Cell Line:	GSI-1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove exon 1. The absence of transcript was confirmed by RT-PCR analysis. (J:130487)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akirin2 Mutation:	22 strains or lines available

Original:	J:130487 Goto A, et al., Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol. 2008 Jan;9(1):97-104
All:	1 reference(s)