Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Cspg4-DsRed.T1)1Akik
Name:	transgene insertion 1, Akiko Nishiyama
MGI ID:	MGI:3796063
Synonyms:	NG2 dsRED, NG2-DsRed, NG2DsRedBAC
Transgene:	Tg(Cspg4-DsRed.T1)1Akik  Location: unknown
Alliance:	Tg(Cspg4-DsRed.T1)1Akik page

Strain of Origin:

(C57BL/6 x SJL)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The transgene construct consisted of the 208 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-309G21, containing the entire NG2 (Cspg4) gene (and 60 kbp of 5' and 114 kbp of 3' flanking sequences), which was modified by inserting an optimized red fluorescent protein variant (DsRed.T1) coding sequence followed by a rabbit beta-globin polyA signal into the first exon of the NG2 gene. The NG2 translation initiation ATG was changed to AAG to prevent translation from the BAC NG2 gene and to allow translation from the first ATG in the DsRed.T1 sequence. (J:129201)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:129201 Zhu X, et al., NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development. 2008 Jan;135(1):145-57
All:	90 reference(s)