Tg(GPD1)A2Bir
Transgene Detail
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| Symbol: |
Tg(GPD1)A2Bir |
| Name: |
transgene insertion A2, Edward H Birkenmeier |
| MGI ID: |
MGI:3795211 |
| Synonyms: |
GPDH-A2 |
| Transgene: |
Tg(GPD1)A2Bir Location: unknown
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| Alliance: |
Tg(GPD1)A2Bir page
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| Strain of Origin: |
(C57BL/6J x LT/Sv)F1
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(GPD1)A2Bir expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
GPD1 (2819) |
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Mutation details: The transgene comprises 12.3 kb of human genomic DNA containing the GPD1 gene, consisting of 3.5 kb of 5' flanking sequence, the 7.6 kb protein-coding region and 1.2 kb of 3' flanking DNA. The 5' flanking sequence includes the proximal and distal promoter regions. Founder line A2 has approximately 14 copies of the transgene. Mice exhibit a much higher level of transgene expression in the cerebral cortex and kidney than is normal for the endogenous gene.
(J:135002)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:135002 Birkenmeier EH, et al., Tissue- and cell-specific expression of human sn-glycerol-3-phosphate dehydrogenase in transgenic mice. Nucleic Acids Res. 1992 Jun 11;20(11):2819-25 |
| All: |
1 reference(s) |
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Analysis Tools
