Tg(GPD1)3Bir
Transgene Detail
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| Symbol: |
Tg(GPD1)3Bir |
| Name: |
transgene insertion 3, Edward H Birkenmeier |
| MGI ID: |
MGI:3795203 |
| Synonyms: |
GPDH-B |
| Transgene: |
Tg(GPD1)3Bir Location: unknown
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| Alliance: |
Tg(GPD1)3Bir page
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| Strain of Origin: |
(C57BL/6J x SJL/J)F2
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(GPD1)3Bir expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
GPD1 (2819) |
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Mutation details: The transgene comprises 12.3 kb of human genomic DNA containing the GPD1 gene, consisting of 3.5 kb of 5' flanking sequence, the 7.6 kb protein-coding region and 1.2 kb of 3' flanking DNA. The 5' flanking sequence includes the proximal and distal promoter regions. Founder line 3 (GPDH-B) has approximately 4 copies of the transgene. The transgene is expressed at higher levels in the cerebral cortex and kidney than the endogenous gene.
(J:135002)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:135002 Birkenmeier EH, et al., Tissue- and cell-specific expression of human sn-glycerol-3-phosphate dehydrogenase in transgenic mice. Nucleic Acids Res. 1992 Jun 11;20(11):2819-25 |
| All: |
1 reference(s) |
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Analysis Tools
