Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrastm1Mok
Name:	neuroblastoma ras oncogene; targeted mutation 1, Moyota Katsuki
MGI ID:	MGI:3794957
Synonyms:	N-ras-
Gene:	Nras  Location: Chr3:102965643-102975230 bp, + strand  Genetic Position: Chr3, 45.25 cM
Alliance:	Nrastm1Mok page

Germline Transmission:	Earliest citation of germline transmission: J:135610
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 and 2 were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on E11.5 embryo extracts. (J:135610)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Nras Mutation:	44 strains or lines available

Original:	J:135610 Nakamura K, et al., Partial functional overlap of the three ras genes in mouse embryonic development. Oncogene. 2008 May 8;27(21):2961-8
All:	2 reference(s)