Gene Expression Data
Assay Details
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Assay
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Reference:
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J:135350
Vizard TN, et al., Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nat Neurosci. 2008 Mar;11(3):285-91
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3794578
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Gene symbol:
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Th
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Gene name:
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tyrosine hydroxylase
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Antibody:
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anti-Th
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Detection system:
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Secondary antibody coupled to Alexa Fluor 594
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Assay notes:
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The eyes were fixed in formalin overnight.
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Results
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Specimen
6C-WT:
postnatal day 1
(more  )
Specimen
6C-WT:
(close  )
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Genetic Background:
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involves: 129X1/SvJ
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Cryosection
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Specimen
6C-HET:
postnatal day 1; Casrtm1Ces/Casr +
(more )
Specimen
6C-HET:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Mutant Allele(s):
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Casrtm1Ces/Casr+
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: iris nerve |
Present |
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6c HET
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There is a small, but statistically insignificant, reduction in sympathetic innervation density in heterozygotes compared to wild type.
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Specimen
6C-KO:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Mutant Allele(s):
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Casrtm1Ces/Casrtm1Ces
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: iris nerve |
Present |
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6c KO
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There is a highly statistically reduction in sympathetic innervation density in homozygotes compared to wild type.
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Specimen
S7-WT:
postnatal day 1
(more )
Specimen
S7-WT:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Cryosection
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Specimen
S7-KO:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Mutant Allele(s):
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Casrtm1Ces/Casrtm1Ces
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Cryosection
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Analysis Tools
