Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Abcc5tm1Bor
Name:	ATP-binding cassette, sub-family C member 5; targeted mutation 1, Piet Borst
MGI ID:	MGI:3794119
Gene:	Abcc5  Location: Chr16:20150053-20245144 bp, - strand  Genetic Position: Chr16, 12.41 cM
Alliance:	Abcc5tm1Bor page

Germline Transmission:	Earliest citation of germline transmission: J:135561
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.5 kb segment of genomic DNA containing exon 17 that encodes amino acids 678 to 745 of the first ATP-binding domain was replaced with a hygro cassette. The absence of protein product was confirmed by western blot analysis on erythrocye vesicle extracts. (J:135561)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcc5 Mutation:	141 strains or lines available

Original:	J:135561 de Wolf CJ, et al., cGMP transport by vesicles from human and mouse erythrocytes. FEBS J. 2007 Jan;274(2):439-50
All:	4 reference(s)