Tg(Myh6-Gsk3b*S9A)1Eno
Transgene Detail
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| Symbol: |
Tg(Myh6-Gsk3b*S9A)1Eno |
| Name: |
transgene insertion 1, Eric N Olson |
| MGI ID: |
MGI:3793718 |
| Synonyms: |
GSK-3betaS9A |
| Transgene: |
Tg(Myh6-Gsk3b*S9A)1Eno Location: unknown
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| Alliance: |
Tg(Myh6-Gsk3b*S9A)1Eno page
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| Strain of Origin: |
C57BL/6 x CBA
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Myh6-Gsk3b*S9A)1Eno expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Gsk3b (MGI:1861437) |
Transgene codes for a protein with a serine to alanine mutation. |
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Mutation details: A cDNA encoding mouse hemagglutinin-taggged GSK-3 with a serine-to-alanine mutation at position 9 was cloned into a cardiac-specific expression plasmid containing the alpha-myosin heavy chain (MHC) promoter and human GH (hGH) poly(A) signal.
(J:73985)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:73985 Antos CL, et al., Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):907-12 |
| All: |
3 reference(s) |
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Analysis Tools
