Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | Notes | References

Symbol:	Fgf16tm1.1(cre)Sms
Name:	fibroblast growth factor 16; targeted mutation 1.1, Suzanne L Monsour
MGI ID:	MGI:3790784
Synonyms:	Fgf16IRESCre
Gene:	Fgf16  Location: ChrX:104807885-104818545 bp, + strand  Genetic Position: ChrX, 47.2 cM, cytoband C3
Alliance:	Fgf16tm1.1(cre)Sms page

Germline Transmission:	Earliest citation of germline transmission: J:139718
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Fgf16tm1.1(cre)Sms expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Fgf16 (MGI:1931627)   Mutation details: Cre recombinase is expressed from this allele under control of the endogenous Fgf16 promoter in the developing cristae and spiral prominence epithelial precursors of the inner ear. The Cre recombinase coding sequence, preceded by an internal ribosomal entry site (IRES) and followed by a single frt site (marking the site of excision of a frt-flanked neomycin resistance cassette), interrupts the first exon of Fgf16 so that codon 63 is disrupted. (J:139718)

Activity:	Tissue activity of this recombinase allele
Driver:	Fgf16 (mouse) Summary of all recombinase alleles driven by Fgf16. Comparative matrix view of recombinase activities Alliance mouse Fgf16 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf16 Mutation:	4 strains or lines available

Original:	J:139718 Hatch EP, et al., Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium. Dev Dyn. 2009 Feb;238(2):358-66
All:	2 reference(s)