Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-B2m)9Mdos
Name:	transgene insertion 9, H Michael Dosch
MGI ID:	MGI:3790767
Synonyms:	GFAP-B2m
Transgene:	Tg(GFAP-B2m)9Mdos  Location: unknown
Alliance:	Tg(GFAP-B2m)9Mdos page

Strain of Origin:

NOD/ShiLtJ

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(GFAP-B2m)9Mdos expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse B2m (MGI:88127)   Mutation details: The transgene consists of the human GFAP promoter fused to murine Beta-2 microglobulin, B2m. Six founders resulted from the microinjection of the GFAP-B2m construct into NOD/LtJ oocytes. Founder Western blot analysis and histological analysis of brain, specifically astrocytes and pancreas, specifically the peri-islet Schwann cells, from transgenic animals confirmed transgene expression. (J:135214)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:135214 Tsui H, et al., Targeting of pancreatic glia in type 1 diabetes. Diabetes. 2008 Apr;57(4):918-28
All:	1 reference(s)